think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. 2005-2023Everyday Health, Inc., a Ziff Davis company. Do your OB rooms have an on call service you can call? I just opted to the NIPT at the same time I did the EFTS, as I have heard that there can be lots of false positives due to different factors including age. Repeated the test and no issues! Analysis of genes involved in drug metabolism and hypersensitivity, allowing clinicians to prescribe with confidence. She should hopefully have a happy healthy baby now.. Hi guys, currently in the same boat. I actually have an auto immune disease so they think thats why. The #1 app for tracking pregnancy and baby growth. Here are 3 factors that can lead to such a result. I wouldn't necessarily do the amnio for that if the baby is otherwise healthy. Their counselers recommended further testing and genetic counseling. Anyone else have this come up? To complete all the standard tests which came back fine and were able to identify that it was a boy but again, suspect maternal abmormality involving X chromosomes. Good luck! I'm not sure who it was but scroll back a bit and i'm sure you'll find it! I hope your 3rd test will give you the 4% you need! The #1 app for tracking pregnancy and baby growth. Please whitelist our site to get all the best deals and offers from our partners. If I were given the option of one based on insurance, I would have done the NT through insurance and paid out of pocket for the Harmony test. I hope your quad screen is conclusive so you get some answers. MaterniT21 positive for Down Syndrome. For some patients, however, results are not reported because of laboratory technical issues such as low fetal fraction and sequencing failures. This type of result is called uninformative, indeterminate, inconclusive, or ambiguous. Just thought I'd update you or anyone else who may read this board. Crossing all fingers and toes its just a lab error. It actually doesn't stay in your system that long. Please specify a reason for deleting this reply from the community. A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. I would request PaPPa and hcg and NT screen which is the triple screen. No problems and the procedure was not nearly as bad as I thought. The performance of NIPT is affected by several factors including maternal obesity, which results in a greater rate of no-calls for obese pregnant women. Find advice, support and good company (and some stuff just for fun). Has anyone had their results come back inconclusive? POSITIVE PREDICTIVE VALUE CALCULATOR FOR NIPT RESULTS https://www.perinatalquality.org/Vendors/NSGC/NIPT/, *I highly suggest you first read through everything in main post located here to start: https://www.reddit.com/r/NIPT/comments/ecjj5v/welcome_to_rnipt_the_sub_for_abnormal_nipt/, *After this head over to this post about the actual individual results: https://www.reddit.com/r/NIPT/comments/itmyjw/my_nipt_results_show_this_abnormality_what_does/. My intention is that you have as much information about what may be going on and can make informed decisions with your treatment team moving forward. GAH! Genetic tests are frequently not covered by Medicare or private health insurance, Every sample from a patient is tested to determine whether there is sufficient feto-placental DNA to provide a reliable result. Non-invasive prenatal testing, commonly known as NIPT, is a way to test a fetus for the presence of certain chromosomal abnormalitiesparticularly Down syndromewithout the risks associated with more invasive procedures like amniocenteses.The necessary information can be obtained from a sample of the mother's blood, which contains some of the fetus' DNA. When the test is repeated, about 1 in 3 repeat NIPT samples comes back with no result. 5/30: 4th beta: 17,852 + saw fetal pole and heard heartbeat! I'm wondering if because I'm a plus size mother? When cells break down, they release . They all came back negative ! Wouldn't that give you the results you're looking for? Please whitelist our site to get all the best deals and offers from our partners. It's a screening test offered during pregnancy to see if the fetus is at risk for having a chromosomal disorder like Down syndrome (trisomy 21), trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome). This educational content is not medical or diagnostic advice. Molecular tests also check for certain changes in a gene or chromosome that may cause or affect the chance of developing a specific disease or disorder, such as cancer. We strive to provide you with a high quality community experience. We aim to be fair and reasonable with our fee structure. To help you get started read our. May 2016. Some chromosome conditions NIPT cannot screen for include: Heart defects Abdominal wall defects Makes me worried about why they can't pick up enough fetal DNA. unfortunately, I called the company and they won't give me any information! But I wish you all the best! Which made me really nervous, would that really be necessary, when my other results (the NT and efts) were fine with low risks? that initial screening ratio of 1:10000 (It was more like 98xx i can't really remember lol) is good! NIPT analyzes fragments of the baby's DNA found circulating in a pregnant person's blood. Just tonight I found out the second draw of blood for the Harmony. 2005-2023Everyday Health, Inc., a Ziff Davis company. Ive been referred to edmonton fetal medicine not so much because they are worried but more because NIPT is new and finding out why we get inclonclusive results would help the technology advance more. I don't know what to do now? Research suggests that about 5 percent of women get no result at all. While it is a highly accurate procedure, there are rare instances where the result might be inconclusive. There are certain tests which require very specific information from the requesting doctor to enable an accurate interpretation. Reasons behind an inconclusive prenatal paternity test. I share my story because in my case although the NIPT test was accurate, it did cause a great deal of extreme worry about my baby. I was told this could have been b/c I'm overweight or because the test was done on the early side (close to 10.5w). Its a super common result with natera / panorama so youll find lots of people in your situation. This is unlikely to be a lab mistake. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. One such factor is high maternal weight. Thanks for sticking with us for a full year. I am overweight so that may be a contributing factor, although my OB was still very very surprised since she has had very few patients of any size receive an inconclusive result. I could have written this myself. The user and all related content has been deleted. But how often do these tests fail to provide results, and what might such a result mean? I got the panerama test at 11 weeks with my second baby. Just got my 2nd no result today. Hoping all is ok. Please place POST FLAIR on your actual post. Noninvasive prenatal testing (NIPT), is a screening test for determining the risk of certain chromosomal abnormalities in the fetus. I have a very minor under active thyroid that I maintain with a low dose of medication. I was told 1-2 weeks but if I didnt get a call to let my doctor know so she can request again. your gp will sort it out for you love. Noninvasive prenatal testing (NIPT) has become popular with many physicians in screening pregnant patients. Im barely 53, but I have about a half an inch in my older sister and come. However, they got all the ones they needed for the NIPT which were good. They told me there wasn't enough fetal DNA in my blood to accurately complete the test. 2) NIPT tests are more accurate and test for MORE genetic disorders (they also tell you sex, if you want to know). Reasons behind an inconclusive prenatal paternity test. Normal chromosomes come. Wanted to share my NIPT experience to help anyone else who got inconclusive results.I first took my NIPT test at 10 weeks on Sept. 30. It's just the not knowing and then always hearing the word "probability"! Please also place a flair on your username which can be done by going to the right side of the sub -- community options -- and update username flair. There was another post on here about the same issue. Now is the perfect time to start your Baby Registry! Ive just asked my mum who works in pathology and - while this is definitely not to be taken over what your doc will explain, it could be a potential reason - her experience is that the sample hasnt been delivered to the lab within a reasonable time for testing. But higher weight makes NIPT more likely to come back with a "no call" result (although generally not until >180 kg). I finally decided to do the Amnio yesterday and now anxiously waiting forresults and am so scare for her to even be Mosaic Turner. So, a "normal" NIPT result doesn't guarantee a healthy baby, and an "abnormal" result doesn't mean your baby definitely has a certain condition. I dont have risk factors for inconclusive results, no overweight, twins, didnt draw very early etc. I hope this helps you consider an alternative, less stressful reason. So I spent around 5 days suffering because of google. Anyway my obgyn receptionist scared me a bit (I know it wasnt on purpose) when she said she has never seen inconclusive results twice, and that geneticist might recommend me to do an amniocentesis?? I believe she had it done only twice. Seems unfair to leave you in limbo not knowing. Thank you, I am hoping it's just a silly lab error. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. How far along are you currently? The DNA sample of the potential father is collected through a buccal swab, and the two samples are compared to determine paternity. NIPT differs from conventional prenatal screening methods in two important ways. Defining the genetic relationship between people or tissue samples using DNA markers. My OB says she sees it all the time and they usually resolve themselves. Prediction of other SCA was more accurate. I'm so sorry to hear about your first trimester screening. Start by selecting which of these best describes you! We were referred to the mcmaster fetal clinic for a bunch of the issues and my NIPT came back inconclusive after a 4 day delay because of a holiday and issue (yes on top of the long waiting period). jenesiso member. The #1 app for tracking pregnancy and baby growth. I'm due 1/2015 and AMA (38). Thanks, I'm still waiting! Science has produced many safe, medically sound, and accurate methods to determine the sex of a fetus during pregnancy. It has to be at least above 4 percent to give a conclusive result. This is a newish kind of screening test in which a blood sample from a pregnant woman is used to test for a range of genetic conditions in the fetus, with varying levels of certainty. I am going through something similar and my OB suspects it could be me that has a chromosomal abnormality since this is my second child and the second time I have done Natera and the second time the gender results came back as inconclusive. Get weekly updates on baby and your body. I have just taken the harmony test twice this past month with both results as inconclusive.. Hi! They said I can get retested and said maybe cause blood had to fly from nz to au? Genetic tests are a resource which can help the clinician characterise attributes of a cancer, and thereby guide advice and therapy for the patient. Anyone else experienced this? Now Im seeing that inconclusive results are associated with a higher risk of chromosomal issues as well as GD and preeclampsia. The waiting is almost unbearable. Nipt test inconclusive twice - Page 2: Has anyone had the test come out inconclusive twice? Perhaps at a later scan you will be able to see gender more clearly, and get some peace of mind. The test can also determine the sex of the fetus. for the test to get accurate results. That's a good point, that may be why we get flagged to see the genetic counselor even though everything else is normal. We are repeating the assay on the same sample you have already sent and we should have that result on Wednesday. My advice: dont look at it. Are you going to have amnio? I got the results yesterday and another inconclusive. Our commitment to quality means that we will only provide a result when there is very clear evidence for, or against, the presence of a specific disorder. info@sonicgenetics.com.au 1800 010 447 (Australia only) 1800 515 119 Of course, this can be dispelled with subsequent retests. TX: IUI #1 with Follistim. Just got this email from the lab doing my test!!! Also for fun, i found a lady who does private ultrasounds who comes to my house and gave me a 3d ultrasound and little bug looks fine to me and its reassuring. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. I'll do my 3rd test at nearly 16 weeks. NIPT (also called prenatal cell-free DNA screening) is a screening test that estimates the risk that your baby will be born with a genetic abnormality, including Down syndrome . After the many concerns my daughter ended up just perfect. Your story is wonderful. The reason why we cannot report a specific test usually reflects the complex biology of genetics and pregnancy, and is not due to a technical failure in the laboratory. It could either actually be me (and could it be passed down? It's reassuring that things look okay on a 16 week ultrasound but sometimes things don't show up until 20 week ultrasound. Its been very interesting learning this for sure and although my symptoms are extremely mild and nothing showed up for my daughters testing last year when I was pregnant with her I still of course hope this wasnt passed down. I believe the odds of retest are actually 5%? Group Black's collective includes Essence, The Shade Room and Naturally Curly. Just pooping in about the initial ratio1:10000 is fabulous! Both said due to low fetal DNA at 2.6% and 2.7% respectively. NIPT Test Results Inconclusive! Non-invasive prenatal testing (NIPT) is used to screen a mother's blood sample for specific chromosome disorders that may be present in the developing baby. It happened to me with my blood results from the triple screening. :). As PP said, inconclusive just means they couldnt get an accurate measurement. This discussion is archived and locked for posting. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Don't despair if your grandmother's wisdom turns out to be little more than a good guess. Just tonight I found out the second draw of blood for the Harmony test came back inconclusive. Symptmes de grossesse ne jamais ignorer, Moyens naturels pour dclencher l'accouchement. Thus, if you received no result during your non-invasive prenatal paternity test, then it might be best to check if any of these 3 factors might be in play. Costs about 50 bucks. . Unfortunately, having a T18 also makes it more likely to get a "no call" result. Below this, the nipt returns the result "inconclusive." after the nipt results: Inconclusive sca an inconclusive sca. Keep us posted! This updates the flair on your username IN THIS SUB ONLY. Thanks! And what was your BMI? Did you get a conclusive test result in the end? Meet other parents of December 2019 babies and share the joys and challenges as your children grow. Hooray I hope everyone else in limbo gets good results too! Has someone fallen into such situation? This testing analyzes small fragments of DNA that are circulating in a pregnant woman's blood. Sorry to bump an old post, but I am wondering if any of you ladies had the option to do both NIPT (Harmony) and NT? It can be caused by being plus sized.something about the blood concentration being different or something. I'm waiting on my nipt test results now too. Hopefully will have before weds next week. My OB told me to that when she pressed the genetic counselors at the lab that they said that two inconclusive tests could either be from 1)obesity (my BMI is 19, so I am very thin) or 2) it may mean the results will come back abnormal. Sounds right on the money, I got turned away for my first babys boot as it was a Friday an they send the test on the Monday and they said they would have it sitting there all weekend its not recommended. There are some options filled in, but you can also write in your own result. I wish you and your baby boy all the best too! Im 20 years old Microarray (rare duplication? Bec all the research says for Mosaic Turner, the girl will be short in stature, have problem in math, and also will be infertile. 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